7 Best NR Supplements Of 2026: Lab Tested & Reviewed

Featured Partner Offer ReadyRx NAD+ Boost brain performance, reduce fatigue, and enhance recovery with revitalizing cognitive Promote cellular repair and healthy aging with anti-aging compounds Doctor prescribed, concierge support, free shipping direct to your door Shop Now On ReadyRx's Website Best NR Supplements of 2026 PartiQlar Pure NR Best Overall 5.0 Rating Our ratings take into account a product's rewards, fees, rates and other category-specific attributes. All ratings are determined solely by our editorial team. Best Overall Cost per serving: $0.92 NR per serving: 500 milligrams NAD+ precursor: Nicotinamide riboside (NR) Other noteworthy ingredients: N/A Our Expert Review Pros & Cons Lab Testing Results Our Expert Review Our research found that PartiQlar Pure is the best NR supplement overall, earning a 5-star rating from our research team. The supplement is manufactured in an FDA-registered, CGMP-and NSF-certified facility, and third-party tested for quality and safety by Certified Laboratories. A standout feature of PartiQlar's Pure NR is its purity. The product features 99% of NR, containing less than 1% impurities. Certificates of analysis (COAs) are available for each product on its website along with clear labeling, contributing to the company's transparency. Customer service is another highlight, with an average Trustpilot user rating of 4.2 stars among over 500 reviewers. Pros and Cons of PartiQlar Pure NR Manufactured in FDA- and NSF-registered facilities Pricier than other products on this list60-day return policy only applies to unused and sealed products Vegan-friendly, containing no fillers or binders Does not contain artificial colors, flavors or preservatives Lab Testing Results Testing insights: Heavy metals (arsenic, cadmium, mercury, lead): Within set safety limits Within set safety limits Microbials: E. coli, aerobic bacteria, yeast and mold, enterobacteria and salmonella not detected or absent Read more See third-party laboratory testing results here. Read More Tru Niagen 300mg Best for Product Transparency 4.7 Rating Our ratings take into account a product's rewards, fees, rates and other category-specific attributes. All ratings are determined solely by our editorial team. Best for Product Transparency Cost per serving: $1.63 NR per serving: 300 milligrams NAD+ precursor: Nicotinamide riboside (NR) Other noteworthy ingredients: N/A Our Expert Review Pros & Cons Lab Testing Results Our Expert Review Our research found that Tru Niagen 300mg is the best NR supplement for product transparency, earning a 4.7-star rating from our research team. The supplement earned Forbes Health's highest score among NR supplements for brand reputation, mirroring the company's effort to go above and beyond to test its products and provide third-party validation. One feature that speaks to Tru Niagen's commitment to product safety and transparency is that you can look up the specific COA using for your exact product by using the lot number (located on the bottom of the bottle) directly through the company's website. Pros and Cons of Tru Niagen 300mg Contains a patented formula of NR which has been used in clinical trials More expensive than most of the other products on this list FDA-notified GRAS, meaning the company has provided product safety data to the FDA According to the company's return policy, customers can only return unopened products within 30 days of purchase Vegetarian, Halal and Kosher Lab Testing Results Testing Insights: Heavy metals (arsenic, cadmium, mercury, lead): Within set safety limits Within set safety limits Microbials: E. coli, aerobic bacteria, yeast and mold, enterobacteria and salmonella not detected or absent Read more See lab testing results here. Read More Renue by Science Lipo NR Best for Product Purity 4.5 Rating Our ratings take into account a product's rewards, fees, rates and other category-specific attributes. All ratings are determined solely by our editorial team. Best for Product Purity Cost per serving: $0.72 NR per serving: 300 milligrams NAD+ precursor: Nicotinamide riboside (NR) Other noteworthy ingredients: N/A Our Expert Review Pros & Cons Lab Testing Results Our Expert Review Our research found that Renu by Science's Lipo NR is the best NR supplement for product purity, earning a 4.5-star rating from our research team. Each batch undergoes a multi-step process to ensure ingredient purity, including raw material verification, independent raw material testing, and potency checks of the final product (using randomly selected bottles). Renu's products are third-party tested in ISO-Certified and CGMP certified labs for quality, purity and potency and manufactured according to pharmaceutical-grade testing standards (the same quality control used for prescription medications). COAs can be accessed on the website. Additionally, the raw material supplier (Effepharm) is disclosed, contributing to ingredient transparency. Pros and Cons of Renue by Science Lipo NR Manufactured in an FDA-registered facility under CGMP standards Advertising emphasizes liposomal NR, which has not been proven to be more effective than standard NR Has a 4.3-star Trustpilot rating based on more than 200 reviews COA lookup by batch number was not available on the website at the time of publishing Free from artificial colors, flavors and preservatives Lab Testing Results Testing insights: Heavy metals (arsenic, cadmium, mercury, lead): Within set safety limits Within set safety limits Microbials: E. coli, aerobic bacteria, yeast and mold, enterobacteria and salmonella not detected or absent Read more See lab testing results here. Read More Auivty NAD+ Nicotinamide Riboside with Resveratrol Best for Affordability 4.4 Rating Our ratings take into account a product's rewards, fees, rates and other category-specific attributes. All ratings are determined solely by our editorial team. Best for Affordability Cost per serving: $0.22 NR per serving: 500 milligrams NAD+ precursor: Nicotinamide riboside (NR) Other noteworthy ingredients: Quercetin phytosome (sophora japonica extract and phospholip Our Expert Review Pros & Cons Lab Testing Results Our Expert Review Our research found that Auivty NAD+ Nicotinamide Riboside with Resveratrol is the best NR supplement for affordability, earning a 4.4-star rating from our testing team. At just $9.99 for a container with 45 servings, Auivty contains 500 milligrams of NR hydrogen malate and is sourced from a GMP-certified facility. In addition to NR, Auivty also contains trans-resveratrol, which has been studied for potential anti-inflammatory and antioxidant properties, and quercetin phytosome, another supplement that may be appealing to those seeking an antioxidant-rich supplement. Pros and Cons of Auivty NAD+ Nicotinamide Riboside with Resveratrol Most affordable option on this list Information about the company isn't readily available outside Amazon, where it's exclusively sold Manufactured in a CGMP facility Supplement facts label features incorrect serving size Rated an average of 4.5 stars on Amazon among over 300 reviewers Lab Testing Results Testing insights: Heavy metals (arsenic, cadmium, mercury, lead): Within set safety limits Within set safety limits Microbials: E. coli, aerobic bacteria, yeast and mold, enterobacteria and salmonella not detected or absent Read more See lab testing results here. Read More Thorne NiaCel 400 Best NR Supplement for Athletes 4.4 Rating Our ratings take into account a product's rewards, fees, rates and other category-specific attributes. All ratings are determined solely by our editorial team. Best NR Supplement for Athletes Cost per serving: $1.23 NR per serving: 415 milligrams NAD+ precursor: Nicotinamide riboside (NR) Other noteworthy ingredients: Betaine anhydrous (trimethylglycine) Our Expert Review Pros & Cons Lab Testing Results Our Expert Review Our research found that Thorne NiaCel 400 is the best NR supplement for athletes, earning a 4.4-star rating from our research team. Thorne is considered a reputable supplement and vitamin brand in the U.S., and its NR product may further display the company's commitment to transparency in its ingredients. Thorne NiaCel 400 is NSF-certified for sport, potentially making it a great choice for athletes who want to be certain about the purity of the supplements they're taking. In addition to NR hydrogen malate, Thorne NiaCel 400 contains betaine anhydrous (trimethylglycine), which has also been studied for its potential cellular effects. Pros and Cons of Thorne NiaCel 400 NSF-certified for sport, meaning it's free of banned athletic substances Products returned during 60-day satisfaction guarantee period may be subject to a 25% restocking fee Flexible savings account (FSA) and health savings account (HSA) eligible One of the more expensive products in this ranking Manufactured in a CGMP-certified facility Lab Testing Results Testing insights: Heavy metals (arsenic, cadmium, mercury, lead): Within set safety limits Within set safety limits Microbials: E. coli, aerobic bacteria, yeast and mold, enterobacteria and salmonella not detected or absent Read more See lab testing results here. Read More UNcena NAD+ Nicotinamide Riboside Resveratrol Elite Best Amazon-Only Option 4.2 Rating Our ratings take into account a product's rewards, fees, rates and other category-specific attributes. All ratings are determined solely by our editorial team. Best Amazon-Only Option Cost per serving: $0.42 NR per serving: 1,200 milligrams NAD+ Precursor: Nicotinamide riboside (NR) Other noteworthy ingredients: Trans-resveratrol Our Expert Review Pros & Cons Lab Testing Results Our Expert Review Our research found that UNcena Nicotinamide Riboside Resveratrol Elite is the best Amazon-only NR supplement on our list, containing 1,2000 milligrams of NR per serving (two capsules), earning a 4.2-star rating from our research team. It's also one of the most budget-friendly selections on this list. UNcena is sold solely on third-party websites like Amazon and eBay, with no additional information about the company or brand available at the time of publishing. Although the product's Amazon listing says that UNcena's supplements are made in a GMP-certified facility and each batch is third-party tested, there's no way to confirm this claim, which makes it difficult to trust. Pros and Cons of UNcena Dosage may appeal to individuals seeking a higher NR content UNcena doesn't have a website, so consumers must rely on supplement information on the brand's Amazon page Vegetarian-friendly capsule COAs are not available despite claims of third-party testing Non-GMO and gluten free Lab Testing Results Testing insights: Heavy metals (arsenic, cadmium, mercury, lead): Within set safety limits Within set safety limits Microbials: E. coli, aerobic bacteria, yeast and mold, enterobacteria and salmonella not detected or absent Read more See lab testing results here. Read More Innerbody Labs NAD+ Support Best for High-Dose NMN 4.4 Rating Our ratings take into account a product's rewards, fees, rates and other category-specific attributes. All ratings are determined solely by our editorial team. Best for High-Dose NMN Cost per serving: $2.47 NAD+ precursor: Nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) NMN or NR per serving: 700 milligrams NMN, 400 milligrams NR Other noteworthy ingredients: Betaine anhydrous Shop Now On Innerbody Lab's Website Our Expert Review Pros & Cons Lab Testing Results Our Expert Review Our research found that Innerbody Labs NAD+ Support is the best NMN supplement for high-dose NMN, earning a 4.4-star rating from our research team. Each serving contains 700 milligrams of NMN, the highest dosage on our list. In addition to NMN, the product contains 400 milligrams of NR, another precursor (building block) of NAD+. The formula also contains betaine anhydrous (trimethylglycine), an ingredient commonly included in dietary supplements. The company's commitment to transparency is another standout feature, with up-to-date COAs clearly accessible on the product page. Pros and Cons of Innerbody Labs NAD+ Support Contains no fillers or proprietary blends Pricier than all the brands ranked on this list Returns for partially used items are accepted within 30 days of receipt Suppliers of raw materials are not disclosed Each batch is third-party tested and manufactured in a GMP-certified, FDA-registered facility Lab Testing Results Testing insights: Heavy metals (arsenic, cadmium, mercury, lead): Within set safety limits Within set safety limits Microbials: E. coli, aerobic bacteria, yeast and mold, enterobacteria and salmonella not detected or absent Read more See lab testing results here. Read More Brand Comparison: Best NR Supplements of 2026 Below is an overview of our research team's ratings of the different NR supplements in this ranking, a summary of why they were chosen and prices per serving. Best NR Supplements: Pricing Below is an overview of the different NR supplements in this ranking and their prices per serving as well as price per milligram of NR. NR SUPPLEMENT BRAND PRICE PER SERVING PRICE PER GRAM OF NR PartiQlar $0.92 $1.83 Tru Niagen $1.63 $5.44 Renue by Science $0.72 $2.41 Auivty $0.22 $0.44 Thorne $1.23 $2.97 UNcena $0.42 $0.42 InnerBody Labs $2.47 $6.17 See More See Less NR SUPPLEMENT BRAND PRICE PER SERVING PRICE PER GRAM OF NR PartiQlar $0.92 $1.83 Tru Niagen $1.63 $5.44 Renue by Science $0.72 $2.41 Auivty $0.22 $0.44 Thorne $1.23 $2.97 UNcena $0.42 $0.42 InnerBody Labs $2.47 $6.17 See More See Less Best NR Supplements: Potency and Other Ingredients We've provided a quick overview of the different GRAS status of the NR supplements in this ranking. GRAS status NR SUPPLEMENT BRAND AMOUNT OF NR PER SERVING (IN MILLIGRAMS) OTHER NOTABLE INGREDIENTS PartiQlar 500 milligrams N/A Tru Niagen 300 milligrams N/A Renue by Science 300 milligrams N/A Auivty 500 milligrams Quercetin phytosome (sophora japonica extract and phospholipid complex sunflower), trans-resveratrol Thorne 415 milligrams Betaine anhydrous (trimethylglycine) UNcena 1,200 milligrams Trans-resveratrol InnerBody Labs 400 milligrams B-Nicotinamide mononucleotide (NMN), spermidine, trimethylglycine, proprietary black pepper fruit extract blend See More See Less NR SUPPLEMENT BRAND AMOUNT OF NR PER SERVING (IN MILLIGRAMS) OTHER NOTABLE INGREDIENTS PartiQlar 500 milligrams N/A Tru Niagen 300 milligrams N/A Renue by Science 300 milligrams N/A Auivty 500 milligrams Quercetin phytosome (sophora japonica extract and phospholipid complex sunflower), trans-resveratrol Thorne 415 milligrams Betaine anhydrous (trimethylglycine) UNcena 1,200 milligrams Trans-resveratrol InnerBody Labs 400 milligrams B-Nicotinamide mononucleotide (NMN), spermidine, trimethylglycine, proprietary black pepper fruit extract blend See More See Less Best NR Supplements: GRAS Status and Third-Party Testing We've provided a quick overview of the different GRAS statuses of the NR supplements in this ranking. In the table below, we also provide a quick overview of what stuck out to us about the brand's third-party testing. NR SUPPLEMENT GRAS STATUS NOTES ON THIRD-PARTY TESTING, CERTIFICATIONS OR MANUFACTURING PRACTICES PartiQlar Not advertised Manufactured in FDA-, GMP- and NSF-registered facilities Tru Niagen GRAS, FDA-notified Company goes a step further to make COAs accessible Renue by Science Not advertised Manufactured in an FDA-registered facility under GMP standards Auivty Not advertised N/A Thorne Self-attested GRAS NSF-certified for sport UNcena Not advertised Advertises third-party testing but offers no additional information or proof InnerBody Labs Not advertised Manufactured in a CGMP-certified facilty See More See Less NR SUPPLEMENT GRAS STATUS NOTES ON THIRD-PARTY TESTING, CERTIFICATIONS OR MANUFACTURING PRACTICES PartiQlar Not advertised Manufactured in FDA-, GMP- and NSF-registered facilities Tru Niagen GRAS, FDA-notified Company goes a step further to make COAs accessible Renue by Science Not advertised Manufactured in an FDA-registered facility under GMP standards Auivty Not advertised N/A Thorne Self-attested GRAS NSF-certified for sport UNcena Not advertised Advertises third-party testing but offers no additional information or proof InnerBody Labs Not advertised Manufactured in a CGMP-certified facilty See More See Less NR Supplement Effectiveness: What the Research Shows 'Nicotinamide riboside is one of the better-studied NAD+ precursors, and the evidence consistently shows that it raises NAD+ levels in humans,' says Gary Soffer, M.D., pediatric allergy and immunology physician at Yale Medicine and medical director of Smilow Cancer Hospital at Yale New Haven Health. 'The challenge is that increasing NAD+ has not yet been shown to have meaningful improvements in health, longevity or physical function.' Baljash S. Cheema, M.D., cardiologist and medical director of the Human Longevity Clinic at Northwestern Medicine, says that while it's 'biologically plausible' that supplements that can boost NAD+ levels may be effective for longevity purposes, there isn't enough evidence to suggest that taking an oral supplement will improve your health. 'We have to stay grounded in what the science shows,' says Dr. Cheema, adding that there have been positive findings in animal studies but that, generally speaking, positive results from pre-clinical trials (including animal studies) don't necessarily mean those results will be replicated in human studies. The science on NR supplementation in humans is relatively new (within the last decade) and includes mixed results, making it difficult to decipher benefits other than the fact that NR supplements do increase NAD+ levels. Authors of a 2025 review in Clinical Bioenergetics, which combed over the available research on NR and NMN supplements, concluded the benefits 'appear to be most pronounced in individuals with suboptimal baseline NAD+ levels,' and that 'NR use may offer little advantage beyond increasing blood NAD+ concentrations'. Explore Next-Generation Wellness With NAD+ Explore AgelessRx NAD+ Injection therapy, featuring medical evaluations, individualized treatment recommendations, and ongoing provider support where appropriate. Get Started On AgelessRx's Website Potential Health Benefits of NR Supplements: Who Should Take One? 'While studies in generally healthy adults have been largely disappointing, there are some early signals that NR may benefit specific patient populations,' says Dr. Soffer. He points to small, early research signals that NR supplements may positively affect inflammation, blood pressure and certain neurodegenerative or cardiovascular conditions. This is intriguing, acknowledges Dr. Soffer, but he says it's still 'way too early to decide whether our patients should use a supplement or not.' How to Choose an NR Supplement 'If consumers choose to take an NR supplement, I recommend selecting a product that has undergone independent third-party testing,' says Dr. Soffer. The FDA does not regulate supplements in the same way as prescription medications, which include strict guidelines on manufacturing, drug potency and more. This means that supplement and vitamin companies vary widely in their transparency and quality practices; some choose to outsource testing to third-party companies or validate the safety and purity of their products in different ways.