I've had a kind of tickly throat for a few weeks. So I went to the doctor today.
In my wildest fantasies.. my hospital visit goes something like this:
I want a full respiratory panel, Biofire FilmArray, full allergy panel. And whatever else you got. You want blood? I got blood. Take as much as you like!
…in reality I waited patiently while the doctor poked various implements in to various orifices.
He then decided he would give me some antihistamine. And thenafterI've finished those maybe run a blood antibody test in a few weeks time to see what allergies I might have.
I've come to accept that doctors just don't like diagnostics. They prefer just to try drugs and see if they work1.
This is probably mostly fine, except in the minority of cases when it isn't (Malaria in Maryland,finding SARS-CoV-2). But it's a little baffling from an academic standpoint… where gather evidence before deciding a course of action seems fundamental.
Later I was poking around in thenewly updated Biobaseand found there are247 point-of-care diagnostics companies.And I could only think 'these poor folks are all doomed'.
Of course larger point-of-care companiesCephied/Danaher,bioMérieux, (Bosch?) andothers. Are doing just fine.
But a significant fraction of these 247 companies are smaller startups likeNanoDxdeveloping neat novel technologies:
The technology always seems very interesting, but I think they are ultimately limited by the market.
The larger players have no doubt built the infrastructure to sell into clinics and hospitals. I suspect this is a near impossible sales problem for a startup.
Which is why perhaps you see folks likeSpinChip being acquired by bioMerieux(~$100M), rather than going it alone.
If I was looking at funding a point-of-care diagnostic company. My primary questions would be can try:
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