Liverpool vs. Atletico Madrid odds, prediction: 2026-27 UEFA Champions League picks, best bets for Wednessday

NFL CFB MLB UFC UCL EPL LaLiga Bundesliga Serie A Ligue 1 MLS NWSL NFL CFB MLB UCL EPL LIGA BUND SERIE A LIGUE 1 MLS NWSL The second day of 2026-27 UEFA Champions League play features Liverpool vs. Atletico Madrid on Paramount+. Liverpool, a six-time champion, are looking to reach the finals for the first time since 2021-22. Atletico Madrid, meanwhile, are a three-time runner-up, last reaching the finals in 2016. Liverpool are coming off a fifth-place finish in the English Premier League, while Atletico Madrid were fourth in La Liga in 2025-26. Stream the match live on Paramount+. Kickoff is at 3 p.m. ET from Anfield in Liverpool, England. The latest Liverpool vs. Atletico Madrid odds list Liverpool as the -140 favorites (risk $140 to win $100) on the 90-minute money line, with Atletico Madrid as the +350 underdogs. A draw is priced at +310, and the over/under for total goals is 2.5. Wednesday's match will be on Paramount+, which you can sign up for here. Before you lock in your Liverpool vs. Atletico Madrid picks or make any Champions League predictions, you need to see what proven soccer expert Jon Eimer has to say. Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, he has covered the English Premier League, Champions League, Serie A, the FA Cup, and more. He's been red-hot on his soccer betting picks in 2026, posting a 31-13-2 record and returning over $1,200 of profit on his Champions League picks. He also ended the World Cup on an 11-5-1 run and nailed seven of his past eight EPL spread picks! Anyone who follows him could be way up. Now Eimer has turned his attention to the Liverpool vs. Atletico Madrid match and we can tell you he is leaning Over 2.5 goals. He also has locked in three CONFIDENT best bets, two of which return plus-money, while offering a full breakdown of this Champions League matchup! You ABSOLUTELY need to see his pick and analysis before making any selections of your own. Don't forget to stream the match on Paramount+. So where does all the betting value lie for Liverpool vs. Atletico Madrid in the Champions League? ... Join SportsLine now to see Jon Eimer's picks for Liverpool vs. Atletico Madrid, all from the insider who is on an 31-13 roll (+1200) on Champions League picks! GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE! JOIN NOW